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We actuate with light & magnets, we fold & unfold DNA, we cell-free express proteins, we play with drops, marbles & interfaces, we organize particles, we harness coffee rings.

Microfluidic single-DNA unzipping just published in ChemComm!



Microfluidic single-DNA unzipping just published in ChemComm!
11 June 2013. Our manuscript "Spatially controlled DNA unzipping by microfluidic interface positioning on a molecule perpendicular to a multicomponent flow" has just been published in Chem. Commun.

Abstract. A DNA molecule is rotated under a transversal electric field to be perpendicular to a longitudinal, multicomponent microfluidic flow. Positioning the interface allows us to control DNA unzipping with spatio-temporal resolution. This demonstrates that a microfluidic gradient can be applied at the single molecule level for a dynamic intramolecular stimulation.

Reference:
Spatially controlled DNA unzipping by microfluidic interface positioning on a molecule perpendicular to a multicomponent flow 
N. K. Mani, S. Rudiuk, D. Baigl*
Chem. Commun. 2013, doi : 10.1039/C3CC44016H